STATEMENT OF NEED
Head and neck squamous cell carcinoma (HNSCC) represents a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,630 new cases are diagnosed in the United States annually, and 14,620 people die of the disease (Siegel et al, 2021). Historically, HNSCC has been associated with tobacco and alcohol use; however, infection with high-risk human papillomavirus (HPV) is now recognized as a causative factor for a growing subset of tumors (NCCN, 2020; Chaturvedi et al, 2011). Human papillomavirus–associated oropharyngeal carcinoma is a distinct entity in terms of etiology, biology, and clinical behavior; importantly, it has a more favorable prognosis and might require less intensive therapy. Despite advances and innovations in multimodality treatment and improved understanding of head and neck carcinogenesis, death rates are increasing for cancers of the oral cavity and pharynx overall (0.5% increase per year from 2009 to 2018), and the prognosis for recurrent/metastatic HNSCC remains poor (Siegel et al, 2021; Chang et al, 2017; Pisani et al, 2020).
Medical oncologists, surgical oncologists, radiation oncologists, nurse practitioners, physician assistants, oncology nurses, and other health care professionals involved in the treatment of patients with head and neck squamous cell carcinoma (HNSCC).
Barbara Burtness, MD
Professor of Medicine
Yale School of Medicine
Smilow Cancer Hospital
Lynsey Teulings, NP
Yale New Haven Health
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i3 Health designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 Medical Knowledge/Practice Assessment MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
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American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities approved for AMA PRA Category 1 Credit™ from organizations accredited by ACCME. Physician assistants may receive a maximum of 1.0 hour of Category 1 credit for completing this program.
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Nursing Continuing Professional Development
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Provider approved by the California Board of Registered Nursing, Provider Number 15824, for 1.0 contact hour.
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OCN®, CPHON®, CBCN®, AOCNP®, AOCNS®, and BMTCN® renewal candidates may apply 1 ILNA point toward:
Please note that some of the course content applies to multiple content areas. The numerical value above indicates the maximum amount of points that can be claimed in each domain. The total amount of ILNA points claimed may not exceed the total amount of NCPD awarded from this course.
DISCLOSURE OF RELEVANT FINANCIAL INFORMATION WITH INELIGIBLE COMPANIES
i3 Health endorses the standards of the ACCME and ANCC that require everyone in a position to control the content of a CME/NCPD activity to disclose all financial relationships with ineligible companies that are related to the content of the CME/NCPD activity. CME/NCPD activities must be balanced, independent of commercial bias, and promote improvements or quality in health care. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession.
A conflict of interest is created when an individual has an opportunity to affect CME/NCPD content about products or services of a commercial interest with which he/she has a financial relationship, which therefore may bias their opinions and teaching. This may include receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, stocks, or other financial benefits.
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Relevant financial relationships exist between the following individuals and commercial interests:
The i3 Health planners, reviewers, and managers have nothing to disclose.
Barbara Burtness, MD, discloses that she has served on an advisory board or panel for ALX, AstraZeneca, Cue, Debiopharm, Exelixis, Genentech, Kura, MacroGenics, Merck, Merck KgaA, Nanobiotix, Nektar, Rakuten, and Vaccinex, and as a consultant for Nuvelution. She has received grant and/or research support from Cue Biopharma, Exelixis, Formation, and Merck.
Lynsey Teulings, NP, has no relevant financial relationships to disclose.
i3 Health has mitigated all relevant financial relationships.
INSTRUCTIONS TO RECEIVE CREDIT
In order to receive credit for this activity, participants must:
UNAPPROVED USE DISCLOSURE
i3 Health requires CME/NCPD faculty (speakers) to disclose to attendees when products or procedures being discussed are off-label, unlabeled, experimental, and/or investigational (not FDA approved), as well as any limitations on the information that is presented, such as data that are preliminary or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling.
This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. If you have questions, contact the medical affairs department of the manufacturer for the most recent prescribing information.
The information provided at this CME/NCPD activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a health care provider relative to diagnostic and treatment options of a specific patient’s medical condition.
This activity is supported by an independent educational grant from Merck.
Aggregate participant data will be shared with commercial supporters of this activity.