STATEMENT OF NEED

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy characterized by an accumulation of abnormal immature or partially mature B lymphocytes in the blood and bone marrow (Wyatt et al, 2025). The introduction of targeted oral oncolytic therapies has shifted the treatment landscape for CLL, with oral agents now considered the standard first-line therapy. While these therapies provide an efficacious and convenient option for patients, they are associated with a range of toxicities that necessitate careful monitoring. Pharmacists play a crucial role in providing a comprehensive treatment approach to help navigate medication access, monitor safety and patient response, provide patient education, and optimize adherence (Wyatt et al, 2025; Upchurch & Muluneh, 2024). In this podcast, Kelsey Marciano, PharmD, BCOP, Clinical Pharmacy Specialist at UCHealth, will explore pharmacist-led strategies for treatment selection and toxicity management to optimize CLL care. 

TARGET AUDIENCE

Oncology pharmacists and other pharmacy practitioners involved in the treatment of patients with chronic lymphocytic leukemia (CLL).

LEARNING OBJECTIVES

Upon completion of this activity, participants should be able to:

• Provide informed treatment recommendations as part of the care team to maximize efficacy and minimize intolerance of novel agents in CLL
• Develop evidence-based dose modification and supportive care strategies for managing novel CLL treatment–related toxicities
• Implement pharmacist-led patient education approaches to enhance treatment understanding and promote self-monitoring of adverse events
• Describe the unique role of pharmacists as part of the interprofessional team in enhancing patient care

REGISTRATION

There is no fee to participate in or claim CPE credit for this activity.

PROVIDED BY

JOINTLY ACCREDITED PROVIDER

In support of improving patient care, i3 Health is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Continuing Pharmacy Education

i3 Health has approved this knowledge-based activity for 0.75 ACPE CE hours. The Universal Activity Number for this activity is JA0008128-0000-25-035-H01-P. Pharmacy CE credits can be submitted to the NABP upon successful completion of the activity and the evaluation by providing your NABP ID and DOB, which must be submitted within 60 days of completion. 

DISCLOSURE OF RELEVANT FINANCIAL INFORMATION WITH INELIGIBLE COMPANIES

i3 Health endorses the standards of the ACPE that require everyone in a position to control the content of a CPE activity to disclose all financial relationships with ineligible companies that are related to the content of the CPE activity. CPE activities must be balanced, independent of commercial bias, and promote improvements or quality in health care. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession.

A conflict of interest is created when an individual has an opportunity to affect CPE content about products or services of an ineligible company with which he/she has a financial relationship, which therefore may bias their opinions and teaching. This may include receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, stocks, or other financial benefits.

i3 Health will identify, review, and mitigate all relevant financial relationships that speakers, authors, or planners disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. i3 Health does not endorse any products or services.

Relevant financial relationships exist between the following individuals and ineligible companies:

The i3 Health planners, reviewers, and managers have nothing to disclose.

Kelsey Marciano, PharmD, BCOP, has no relevant financial relationships to disclose. 

i3 Health has mitigated all relevant financial relationships.

INSTRUCTIONS TO RECEIVE CREDIT

In order to receive credit for this activity, participants must listen to the podcast and submit a completed evaluation at the end of the activity.

TECHNOLOGY REQUIREMENTS FOR VIRTUAL CME | NCPD | CPE ACTIVITIES

For virtual (asynchronous, archived live, home study; synchronous webinars) CME/NCPD/CPE activities, include access to system requirements:

• The Internet browser(s) supported and minimum versions of each required by the learner to complete the online activity.
• The minimum memory, storage, processor, and Internet speeds require by the learner to complete the online activity.

UNAPPROVED USE DISCLOSURE

i3 Health requires CME/NCPD/CPE faculty (speakers) to disclose to attendees when products or procedures being discussed are off-label, unlabeled, experimental, and/or investigational (not FDA approved), as well as any limitations on the information that is presented, such as data that are preliminary or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling.

This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. If you have questions, contact the medical affairs department of the manufacturer for the most recent prescribing information.

DISCLAIMER

The information provided at this CPE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

COMMERCIAL SUPPORT

This activity is supported by a medical education grant from BeOne Medicines USA, Inc.

CONTACT INFORMATION

Technical queries or questions regarding activity credit should be directed to i3 Health at support@i3health.com.